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	Provedor de dados Scientia Agricola (1) Autor Balieiro,Julio César Carvalho (1) Coelho,Lia Alencar (1) Martins Junior,Alicio (1) Mingoti,Gisele Zoccal (1) Takada,Luciana (1) Palavra-chave Comet assay (1) Embryos (1) Gonadotropins (1) In vitro fertilization (1) Melatonin (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 48 Primeira ... 1 2 3 ... Última Autoantibody production in chronic idiopathic urticaria is not associated with Helicobacter pylori infection BJMBR Atta,A.M.; Rodrigues,M.Z.A.; Sousa,C.P.; Medeiros Júnior,M.; Sousa-Atta,M.L.B.. Chronic idiopathic urticaria (CIU) is a dermatological syndrome, characterized by raised erythematous skin lesions, that affects 20% of the general population and has been associated with autoimmunity. However, some reports have also suggested a close relationship between CIU and Helicobacter pylori infection, which is endemic in developing countries and associated with chronic gastritis, peptic ulcer disease, and gastric carcinoma. In the present study, we investigated the occurrence of autoantibodies in sera from 23 CIU subjects infected with H. pylori and from 23 CIU subjects without this infection. The presence of anti-thyroid antibodies was determined by indirect hemagglutination assay and the presence of autoantibodies to IgE and C1INH was determined... Tipo: Info:eu-repo/semantics/other Palavras-chave: Chronic idiopathic urticaria; Autoimmunity; Autoantibodies; Helicobacter pylori. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100002 Primary antibiotic resistance and its relationship with cagA and vacA genes in Helicobacter pylori isolates from Algerian patients BJM Bachir,Meryem; Allem,Rachida; Tifrit,Abedelkarim; Medjekane,Meriem; Drici,Amine El-Mokhtar; Diaf,Mustafa; Douidi,Kara Turki. Abstract The epidemiology of Helicobacter pylori resistance to antibiotics is poorly documented in Africa and especially in Algeria. The aim of our study was to determine the antibiotic resistance rates, as well as its possible relationship with VacA and CagA virulence markers of isolates from Algerian patients. One hundred and fifty one H. pylori isolate were obtained between 2012 and 2015 from 200 patients with upper abdominal pain. Antimicrobial susceptibility testing was performed for amoxicillin, clarithromycin, metronidazole, ciprofloxacin, rifampicin and tetracycline. Molecular identification of H. pylori and the detection of vacA and cagA genes were performed using specific primers. We found that H. pylori was present in 83.5% of collected... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Antibiotic resistance; Vaca; Caga; Algeria. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300544 Gene polymorphism of interleukin 1 and 8 in chronic gastritis patients infected withHelicobacter pylori J. Venom. Anim. Toxins incl. Trop. Dis. Caleman Neto,Agostinho; Rasmussen,Lucas T; Labio,Roger W de; Queiroz,Valdeir F de; Smith,Marília de AC; Viani,Gustavo A; Payão,Spencer LM. Background : Epidemiological investigations have indicated thatHelicobacter pyloriinduces inflammation in the gastric mucosa regulated by several interleukins. The genesIL1BandIL8are suggested as key factors in determining the risk of gastritis. The aim of this paper was to evaluate the association of gene polymorphism of interleukin-1 and interleukin-8 with chronic gastrits inH. pyloriinfected patients. A total of 60 patients underwent endoscopic procedure. Biopsy samples were collected for urease test, histopathological and molecular exams. The DNA of theses samples was extracted for detection ofH. pyloriand analysis of the genes mentioned above. Patients with gastritis had a higher frequency ofH. pylori-positive samples.Results : H. pyloriwas detected... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Polymorphism; Interleukin. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200327 Investigation of Helicobacter pylori antigen in stool samples of patients with upper gastrointestinal complaints BJM Calik,Zeki; Karamese,Murat; Acar,Osman; Karamese,Selina Aksak; Dicle,Yalcin; Albayrak,Fatih; Can,Serpil; Guvendi,Bulent; Turgut,Alpgiray; Cicek,Mustafa; Yazgi,Halil. Abstract Helicobacter pylori infection is usually acquired in early childhood and it can persist throughout life without antibiotic treatment. This study aimed to compare the accuracy of the noninvasive H. pylori Stool Antigen Test-applied on the stool samples with the invasive gold standart Rapid Urease Test-applied on the gastric biopy samples of patients with upper gastrointestinal complaints. After endoscopy, biopsy and stool specimens were taken in 122 patients. The infection was detected with rapid urease test which is accepted as gold standart test. Rapid, one-step H. pylori card test was applied to all patients stool specimens. In this study 106 of the 122 patients (86.8%) were positive for H. pylori infection, while 16 of the 122 patients (13.2%)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Upper gastrointestinal complaints; Rapid urease test; H. pylori card test. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000100167 tlpA gene expression is required for arginine and bicarbonate chemotaxis in Helicobacter pylori Biol. Res. Cerda,Oscar A; Núñez-Villena,Felipe; Soto,Sarita E; Ugalde,José Manuel; López-Solís,Remigio; Toledo,Héctor. About half of the human population is infected with Helicobacter pylori, a bacterium causing gastritis, peptic ulcer and progression to gastric cancer. Chemotaxis and flagellar motility are required for colonization and persistence of H. pylori in the gastric mucus layer. It is not completely clear which chemical gradients are used by H. pylori to maintain its position. TlpA, a chemotaxis receptor for arginine/ bicarbonate, has been identified. This study aimed to find out whether tlpA gene expression is required for the chemotactic response to arginine/bicarbonate. Wild-type motile H. pylori ATCC 700392 and H. pylori ATCC 43504, a strain having an interrupted tlpA gene, were used. Also, a tlpA-knockout mutant of H. pylori 700392 (H. pylori 700-tlpA::cat)... Tipo: Journal article Palavras-chave: TlpA; Chemotaxis; Helicobacter pylori; Arginine; Bicarbonate. Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000300009 Comparison of histological and molecular diagnosis of Helicobacter pylori in benign lesions and gastric adenocarcinoma BJM César,Ana Cristina Gobbo; Cury,Patrícia Maluf; Payão,Spencer Luiz Marques; Liberatore,Paula Rahal; Silva,Ana Elizabete. Helicobacter pylori colonization is associated with chronic gastritis, peptic ulcers, intestinal metaplasia, adenocarcinoma and lymphoma of the stomach. The objective of this study was to compare the results of the routinely used histology with molecular diagnosis for the detection of H. pylori. Eighty samples from gastric lesions (chronic gastritis, atrophic gastritis, gastric ulcer, and intestinal metaplasia), 18 gastric adenocarcinoma and 10 normal mucosa H. pylori-negative (control) samples were obtained. All samples were examined histologically (hematoxylin-eosin and Giemsa staining), and PCR amplifications of the species-specific antigen gene (H3H4) and urease A gene segment (H5H6) of H. pylori were made, using the human gene CYP1A1 for DNA quality... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Gastric lesions; Adenocarcinoma; Histological diagnosis; PCR. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000100003 Anti-Helicobacter pylori activity of plant extracts traditionally used for the treatment of gastrointestinal disorders BJM Cogo,Laura Lúcia; Monteiro,Cristina Leise Bastos; Miguel,Marilis Dallarmi; Miguel,Obdulio Gomes; Cunico,Miriam Machado; Ribeiro,Marcelo Lima; Camargo,Eloá Ramalho de; Kussen,Gislene Maria Botão; Nogueira,Keite da Silva; Costa,Libera Maria Dalla. The antibacterial activity of plant extracts obtained from Bixa orellana L., Chamomilla recutita L., Ilex paraguariensis A. St.-Hil., Malva sylvestris L., Plantago major L. and Rheum rhaponticum L. has been evaluated against two reference strains and eleven clinical isolates of Helicobacter pylori. All the plant species chosen are used in popular Brazilian cuisine and folk medicine in the treatment of gastrointestinal disorders. Initial screening was made by the disk diffusion test and then minimum inhibitory concentration was determined by the agar dilution method. The results presented in this work demonstrated that among the plant preparations analyzed, B. orellana L., C. recutita L., I. paraguariensis A. St.-Hil. and M. sylvestris L. were capable of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Antibacterial activity; Plant extracts. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200007 Characterization of virulence genes cagA and vacA in Helicobacter Pylori and their prevalence in gastrointestinal disorders BJM Cogo,Laura Lúcia; Monteiro,Cristina Leise Bastos; Nogueira,Keite da Silva; Palmeiro,Jussara Kasuko; Ribeiro,Marcelo Lima; Camargo,Eloá Ramalho de; Neves,Daniel Locatelli; Nascimento,Aguinaldo José do; Costa,Libera Maria Dalla. Prevalence of H. pylori infection was determined using cultures of gastric biopsy samples of patients attended at the academic hospital of the Federal University of Paraná, Curitiba, Paraná, Brazil. Molecular methods were used to characterize the cagA and vacA genes from bacterial isolates associated with different diseases presented by patients. Out of a total of 81, forty-two gastric biopsy samples tested were positive for H. pylori, with a prevalence of 51.9%. No significant difference was found with regard to the gender (p=0.793) and age (p=0.183) of the patients. Genotype s1m1 vacA gene was found in 67% of the cases of peptic ulcer investigated (p=1.0), despite the limited number of patients with this disease (n=3). A correlation between the presence... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Virulence genes; CagA; VacA. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400007 Eradication of Helicobacter pylori infection in patients with duodenal ulcer and non-ulcer dyspepsia and analysis of one-year reinfection rates BJMBR Della Libera,E.; Rohr,M.R.S.; Moraes,M.; Siqueira,E.S.; Ferrari Jr.,A.P.. Helicobacter pylori (HP) infection is endemic worldwide. The proposed treatment is expensive and there are few reports regarding reinfection rates in Brazil. The aim of this study was to compare the eradication rates obtained with two therapeutic options and to evaluate reinfection one year after treatment. This was a prospective randomized trial with 55 patients. Thirty-nine patients had active duodenal ulcer (DU) and 16 non-ulcer dyspepsia (NUD), and all tested positive for HP. Diagnosis was based on at least two positive tests: ultrarapid urease test, histology and/or culture. Patients were randomized to two groups: group OMC treated with 40 mg omeprazole (once a day), 500 mg metronidazole and 250 mg clarithromycin (twice daily) for 7 days, or group NA... Tipo: Info:eu-repo/semantics/other Palavras-chave: Helicobacter pylori; Peptic disease; Non-ulcer dyspepsia; Gastritis. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600008 In vitro antagonistic activity of Lactobacillus casei against Helicobacter pylori BJM Enany,Shymaa; Abdalla,Salah. Helicobacter pylori is one of the most common causes of chronic infections in humans. Curing H. pylori infection is difficult because of the habitat of the organism below the mucus adherent layer of gastric mucosa. Lactobacilli are known as acid-resistant bacteria and can remain in stomach for a long time than any other organism, we aimed in this study to examine the efficacy of Lactobacillus casei as a probiotic against H. pylori in humans. Particularly, L. casei was opted as it is considered to be one of the widely used probiotics in dairy products. One hundred and seven strains of H. pylori were isolated from dyspeptic patients and were tested for their antibiotic susceptibility to metronidazole (MTZ), clarithromycin (CLR), tetracycline (TET), and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Lactobacillus casei; Probiotics. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401201 Helicobacter pylori Infection is a Significant Factor Risk for Hyperhomocysteinemia in the Patients with Coronary Artery Disease BABT Fallah,Soudabeh; Moradi,Nariman; Reza,Fadaei; Reza,Ahmadi; Azardokht,Tabatabei; Seifi,Morteza. ABSTRACT This work aimed to determine whether seropositivity to Helicobacter pylori infection was an independent risk factor for hyperhomocysteinemia patients with cardiovascular disease. The H. pylori IgG, IgA and homocystein levels in 96 patients with cardiovascular disease and 64 participants free of cardiovascular disease as control subjects were determined by ELISA assay. The results showed that seropositivity to H. pylori IgG and IgA levels of coronary artery disease (CAD)patients was significantly higher than the controls and CAD patients with H. pylori IgG and IgA negative antibodies. A significant correlation was found between the seropositivity to H. pylori IgG and homocysteine levels of CAD patients in comparison with the controls and CAD... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cardiovascular disease; ELISA assay; Homocysteine; Helicobacter pylori. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100304 To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori BJID Hajiaghamohammadi,Ali Akbar; Zargar,Ali; Oveisi,Sonia; Samimi,Rasoul; Reisian,Sedigheh. ABSTRACT Objective: The aim of this study was to evaluate the effect of licorice in H. pylori eradication in patients suffering from dyspepsia either with peptic ulcer disease (PUD) or non-ulcer dyspepsia (NUD) in comparison to the clarithromycin-based standard triple regimen. Methods: In this randomized controlled clinical trial, 120 patients who had positive rapid urease test were included and assigned to two treatment groups: control group that received a clarithromycin-based triple regimen, and study group that received licorice in addition to the clarithromycin-based regimen for two weeks. H. pylori eradication was assessed six weeks after therapy. Data was analyzed by chi-square and t-test with SPSS 16 software. Results: Mean ages and SD were 38.8... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Licorice; Dyspepsia; Peptic ulcer. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600534 Duodenal gastric metaplasia and Helicobacter pylori infection in patients with diffuse nodular duodenitis BJMBR Li,X.B.; Ge,Z.Z.; Chen,X.Y.; Liu,W.Z.. Whether the regression of gastric metaplasia in the duodenum can be achieved after eradication of Helicobacter pylori is not clear. The aim of the present study was to investigate the relationship between H. pylori infection and gastric metaplasia in patients with endoscopic diffuse nodular duodenitis. Eighty-six patients with endoscopically confirmed nodular duodenitis and 40 control patients with normal duodenal appearance were investigated. The H. pylori-positive patients with duodenitis received anti-H. pylori triple therapy (20 mg omeprazole plus 250 mg clarithromycin and 400 mg metronidazole, all twice daily) for one week. A control endoscopy was performed 6 months after H. pylori treatment. The H. pylori-negative patients with duodenitis received 20... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nodular duodenitis; Helicobacter pylori; Gastric metaplasia. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000700002 Helicobacter pylori adhesion to gastric epithelial cells is mediated by glycan receptors BJMBR Magalhães,A.; Reis,C.A.. Helicobacter pylori adhesion to gastric epithelial cells constitutes a key step in the establishment of a successful infection of the gastric mucosa. The high representation of outer membrane proteins in the bacterial genome suggests the relevance of those proteins in the establishment of profitable interactions with the host gastric cells. Gastric epithelial cells are protected by a mucous layer gel, mainly consisting of the MUC5AC and MUC6 mucins. In addition to this protective role, mucins harbor glycan-rich domains that constitute preferential binding sites of many pathogens. In this article we review the main players in the process of H. pylori adhesion to gastric epithelial cells, which contribute decisively to the high prevalence and chronicity of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Bacterial adhesins; Lewis antigens; Glycan receptors; Chronic gastritis; Gastric carcinogenesi. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700002 Lectin staining patterns in human gastric mucosae with and without exposure to Helicobacter pylori BJM Melo-Junior,Mario R.; Cavalcanti,Carmelita L.B.; Pontes-Filho,Nicodemos T.; Carvalho Jr.,Luiz B.; Beltrão,Eduardo I. C.. The aim of the present study was to evaluate qualitative changes in the glycoconjugate expression in human gastric tissue of positive and negative patients for Helicobacter pylori, through lectins: Wheat Germ Agglutinin (WGA) and Concanavalin A (Con A). The lectins recognized differently the glycoconjugates in the superficial mucous layer at the gastric tissues. The results suggest a significant change in the carbohydrate moieties present on the surface of the gastric cells during infection. Tipo: Info:eu-repo/semantics/article Palavras-chave: Lectin; Gastric mucosae; Helicobacter pylori. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000200007 Correlation between Helicobacter pylori infection, gastric diseases and life habits among patients treated at a university hospital in Southeast Brazil BJID Módena,José Luiz Proença; Acrani,Gustavo Olszanski; Micas,André Fernando Ditondo; Castro,Marly de; Silveira,Wanderley Dias da; Módena,José Luiz Pimenta; Oliveira,Ricardo Brandt de; Brocchi,Marcelo. Helicobacter pylori is considered a significant agent in the development of various gastric diseases. However, the diseases caused by this bacterium are known as being multi-factorial, with the genotype, immune system and life habits of the host playing important roles in the establishment of the clinical outcome. Also, H. pylori exhibit a high degree of genetic variability, contributing to the complexity of the host-pathogen relationship. These observations, considered together with the widely-varying origins and social habits of the Brazilian population, lead us to speculate about the influence of these life habits on H. pylori infection and the clinical outcome. Therefore, in this study we evaluated the relationship between H. pylori infection and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Duodenal ulcer; Gastric ulcer; Gastritis; Life habits. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100020 Anti-Helicobacter pylori and Anti-inflammatory Properties of Eugenia uniflora L. BABT Monteiro,Jessica Raquel Borges; Ardisson,Juliana Santa; Athaydes,Brena Ramos; Gonçalves,Rita de Cássia Ribeiro; Rodrigues,Ricardo Pereira; Kuster,Ricardo Machado; Kitagawa,Rodrigo Rezende. Abstract Helicobacter pylori is a bacterium that reaches half of the world population and it’s recognized as the main cause of chronic gastritis and peptic ulcer. In this study, we evaluated the anti-H. pylori, antioxidant and immunomodulatory activities of the methanolic (MeOH) extract of Eugenia uniflora leaves and chemical profile. Anti-H. pylori activity was evaluated by spectrophotometric broth microdilution technique by determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), in addition to the evaluation of the effect on the urease enzyme. The antioxidant activity was evaluated by capturing O2 •-, HOCl e NO• radicals. The immunomodulatory effect was evaluated on the cytokines TNF-α, IL-6 and on nitric... Tipo: Info:eu-repo/semantics/article Palavras-chave: Eugenia uniflora; Helicobacter pylori; Antioxidant; Immunomodulation. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100424 Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk and unpasteurized dairy products in Iran J. Venom. Anim. Toxins incl. Trop. Dis. Mousavi,Soolmaz; Dehkordi,Farhad Safarpoor; Rahimi,and Ebrahim. Background Despite the high importance of Helicobacter pylori, the origin and transmission of this bacterium has not been clearly determined. According to controversial theories and results of previous studies, animal source foods – especially milk – play an important role in the transmission of H. pylori to humans. The aim of the present study was to determine the distribution of vacA, cagA,iceA and oipA virulence factors inH. pylori strains isolated from milk and dairy products and study their antimicrobial resistance properties.Methods A total of 520 raw milk and 400 traditional dairy product samples were cultured and tested. Those that were H. pylori-positive were analyzed for the presence of vacA,cagA, iceA and oipAvirulence factors. Antimicrobial... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Virulence factors; Antibiotic resistance properties; Milk; Dairy products; Iran. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200341 Antimicrobial susceptibility testing for Helicobacter pylori isolates from Brazilian children and adolescents: comparing agar dilution, E-test, and disk diffusion BJM Ogata,Silvio Kazuo; Gales,Ana Cristina; Kawakami,Elisabete. Antimicrobial susceptibility testing for Helicobacter pylori is increasingly important due to resistance to the most used antimicrobials agents. Only agar dilution method is approved by CLSI, but it is difficult to perform routinely. We evaluated the reliability of E-test and disk diffusion comparing to agar dilution method on Helicobacter pylori antimicrobial susceptibility testing. Susceptibility testing was performed for amoxicillin, clarithromycin, furazolidone, metronidazole and tetracycline using E-test, disk-diffusion and agar dilution method in 77 consecutive Helicobacter pylori strains from dyspeptic children and adolescents. Resistance rates were: amoxicillin - 10.4%, 9% and 68.8%; clarithromycin - 19.5%, 20.8%, 36.3%; metronidazole - 40.2%33.7%,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; E-test; Disk diffusion; Susceptibility test. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400039 Ureases display biological effects independent of enzymatic activity: Is there a connection to diseases caused by urease-producing bacteria? BJMBR Olivera-Severo,D.; Wassermann,G.E.; Carlini,C.R.. Ureases are enzymes from plants, fungi and bacteria that catalyze the hydrolysis of urea to form ammonia and carbon dioxide. While fungal and plant ureases are homo-oligomers of 90-kDa subunits, bacterial ureases are multimers of two or three subunit complexes. We showed that some isoforms of jack bean urease, canatoxin and the classical urease, bind to glycoconjugates and induce platelet aggregation. Canatoxin also promotes release of histamine from mast cells, insulin from pancreatic cells and neurotransmitters from brain synaptosomes. In vivo it induces rat paw edema and neutrophil chemotaxis. These effects are independent of ureolytic activity and require activation of eicosanoid metabolism and calcium channels. Helicobacter pylori, a Gram-negative... Tipo: Info:eu-repo/semantics/article Palavras-chave: Urease; Canatoxin; Helicobacter pylori; Inflammation; Neutrophils; Eicosanoids. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000700002 Registros recuperados: 48 Primeira ... 1 2 3 ... Última

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